Vanessa Hall – University of Copenhagen

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Stem cells – basic concepts, disease modelling and lasting therapies

Vanessa Hall

Associate Professor

University of Copenhagen
Department of Veterinary and Animal Sciences
Grønnegårdsvej 7
1870 Frederiksberg C

E-mail: vh@sund.ku.dk
Phone: (+45) 3533 2512

In 2006, Vanessa was appointed as postdoctoral researcher at Lund University in Sweden, and performed reprogramming of mouse adult stem cells. In 2007, she continued a postdoctoral research position at the University of Copenhagen, Denmark to work on porcine embryonic stem cells and, in 2010, she was appointed as Assistant Professor at the University of Copenhagen to continue her interests in porcine stem cell research.

In 2014, she was then appointed as Associate Professor in Anatomy, where she continues her research now in the Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen.

Vanessa Hall’s current primary interests is on modelling Alzheimer’s disease (AD) using induced pluripotent stem cells (iPSCs). She is currently working on two stem cell-related projects. The first includes determining novel mechanisms related to AD in human AD-derived induced pluripotent stem cells. Here she is investigating the role of the nucleolus in the disease and how nucleolar dysfunction may be contributing to the pathology. The second project is focused on making more disease-relevant cell types in the dish for studying AD. In particular, she is interested in producing stellate cells in a dish from iPSCs, which display AD pathology much earlier than other cell types in the brain. In order to gain more information on the growth factors required to produce stellate cells from iPSCs, she is characterizing the entorhinal cortex from the developing pig fetal brain. She has also recently established a neural stem cell model in a pig model of AD.

Vanessa has attracted local funding for her research projects and was awarded the Sapere Aude Elite Award in 2010. She has international relations with groups including, the Norwegian Research School in Neuroscience, Norway and Lund University, in Sweden. Furthermore she has authored more than 45 refereed international publications.